Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11391684 | 0.92 | PDE5A (0.41) | PDE5AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11559725 | 0.90 | TP53 (0.44) | PDE5AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11380547 | 0.88 | MGLL (0.48) | KDM4EALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL11550616 | 0.88 | GUSB (0.51) | KDM4EHPGDHSD17B10NPC1RAB9A | |
| SCHEMBL11375677 | 0.87 | PDE5A (0.54) | PDE5AKDM4EHPGDHSD17B10NPC1 | |
| SCHEMBL11384755 | 0.85 | PDE5A (0.42) | PDE5ANPC1RAB9APOLBTDP1 | |
| SCHEMBL10205331 | 0.85 | TNKS (0.47) | PDE5AKDM4ENPC1TDP1MEN1 | |
| SCHEMBL11552075 | 0.84 | GUSB (0.47) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL11374918 | 0.83 | NPSR1 (0.42) | PDE5AALDH1A1TP53TNKS | |
| SCHEMBL11375179 | 0.82 | PDE5A (0.45) | PDE5AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |