Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389001 | 0.89 | PKM (0.46) | PDE5ACA1CA2ACHETNKS | |
| SCHEMBL11374918 | 0.89 | NPSR1 (0.42) | PDE5ATNKSCHEK2TP53 | |
| SCHEMBL11382937 | 0.86 | PDE5A (0.44) | PDE5A | |
| SCHEMBL11376235 | 0.86 | NPSR1 (0.44) | PDE5ATNKSKMT2ACHEK2MAPT | |
| SCHEMBL11559725 | 0.86 | TP53 (0.44) | PDE5AKMT2ACHEK2POLBTP53 | |
| SCHEMBL11390124 | 0.85 | PDE5A (0.41) | PDE5ATNKSKMT2ANPC1POLB | |
| SCHEMBL11386259 | 0.84 | PDE5A (0.53) | PDE5AKMT2A | |
| SCHEMBL11550616 | 0.83 | GUSB (0.51) | TNKSCHEK2NPC1POLBRAB9A | |
| SCHEMBL11375677 | 0.83 | PDE5A (0.54) | PDE5ATNKSKMT2APKMNPC1 | |
| SCHEMBL11552075 | 0.80 | GUSB (0.47) | KMT2ACHEK2POLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |