Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11552075 | 0.91 | GUSB (0.47) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11374443 | 0.91 | GUSB (0.53) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11556538 | 0.91 | TSHR (0.47) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11554058 | 0.91 | GUSB (0.51) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11550616 | 0.91 | GUSB (0.51) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11552873 | 0.89 | PDE5A (0.44) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11549969 | 0.89 | GUSB (0.49) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11380547 | 0.89 | MGLL (0.48) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11375402 | 0.88 | AMY1A (0.50) | GUSBTP53POLBMAPTTDP1 | |
| SCHEMBL11550692 | 0.87 | LMNA (0.43) | GUSBTP53POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | claimed |
| US-4251531-A | ANTIALLERGENS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1981-02-17 | — | — | US | disclosed |