Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550603 | 0.92 | GUSB (0.47) | LMNASMN1; SMN2NPSR1GUSBMAPT | |
| SCHEMBL11551327 | 0.90 | ALDH1A1 (0.49) | LMNASMN1; SMN2NPSR1GUSBMAPT | |
| SCHEMBL11556538 | 0.88 | TSHR (0.47) | SMN1; SMN2GUSBMAPTTP53POLB | |
| SCHEMBL11375670 | 0.87 | GUSB (0.56) | LMNASMN1; SMN2NPSR1GUSBMAPT | |
| SCHEMBL11552873 | 0.87 | PDE5A (0.44) | LMNAGUSBMAPTTP53POLB | |
| SCHEMBL11553482 | 0.86 | BRD4 (0.40) | LMNASMN1; SMN2NPSR1GUSBMAPT | |
| SCHEMBL11550702 | 0.84 | GUSB (0.42) | SMN1; SMN2GUSBMAPTTP53POLB | |
| SCHEMBL11556986 | 0.84 | KMT2A (0.44) | LMNASMN1; SMN2NPSR1MAPTPOLB | |
| SCHEMBL11552075 | 0.83 | GUSB (0.47) | LMNAGUSBMAPTTP53POLB | |
| SCHEMBL11554058 | 0.82 | GUSB (0.51) | LMNAGUSBMAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | claimed |
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |