Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | IL17A | Q16552 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551327 | 0.87 | ALDH1A1 (0.49) | NPSR1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11553482 | 0.86 | BRD4 (0.40) | KMT2ANPSR1KDM4EALDH1A1MAPT | |
| SCHEMBL11557400 | 0.86 | NPSR1 (0.47) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL11550692 | 0.84 | LMNA (0.43) | NPSR1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL11549502 | 0.79 | MEN1 (0.46) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL11550603 | 0.77 | GUSB (0.47) | NPSR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL11552873 | 0.74 | PDE5A (0.44) | KMT2APOLBMAPTLMNACHEK2 | |
| SCHEMBL11556538 | 0.73 | TSHR (0.47) | KMT2AMEN1KDM4EALDH1A1POLB | |
| SCHEMBL11550624 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL11375670 | 0.72 | GUSB (0.56) | NPSR1KDM4EPOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159330-A | ANTIALLERGENS | CARLO ERBA S.P.A. (IT) | 1979-06-26 | — | — | US | disclosed |