Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620900 | 0.89 | ASIC3 (0.44) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11548721 | 0.85 | HAO1 (0.43) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11556810 | 0.84 | MAPT (0.38) | HAO1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11216394 | 0.84 | ASIC3 (0.41) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11552961 | 0.83 | HAO1 (0.49) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11554919 | 0.83 | HAO1 (0.49) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11556176 | 0.80 | HAO1 (0.44) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL12391039 | 0.79 | ASIC3 (0.50) | HAO1LMNAL3MBTL1MAPTASIC3 | |
| SCHEMBL11298069 | 0.79 | HAO1 (0.49) | HAO1LMNAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11300267 | 0.79 | HAO1 (0.49) | HAO1LMNAL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151294-A | Alkynols and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |