Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295121 | 0.98 | SMN1; SMN2 (0.43) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL8535478 | 0.83 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2CYP1A2ATMMEN1 | |
| SCHEMBL2242665 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL28998684 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL1090112 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL8422457 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL778332 | 0.80 | SMN1; SMN2 (0.52) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL2453047 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL9073359 | 0.78 | HRH1 (0.56) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM | |
| SCHEMBL9336873 | 0.78 | HRH1 (0.50) | ALDH1A1TP53SMN1; SMN2CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001981-A1 | 9-(Omega-heteroarylamino-alkylamino)-erythromycins, their salts, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1979-05-30 | — | — | EP | disclosed |