Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295121 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2MAPK1LMNATSHR | |
| SCHEMBL11552038 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2CYP1A2MAPK1LMNATSHR | |
| SCHEMBL1308905 | 0.82 | MAPT (0.61) | SMN1; SMN2MAPK1LMNAHTTALDH1A1 | |
| SCHEMBL38827 | 0.82 | MAPT (0.57) | SMN1; SMN2MAPK1LMNAHTTALDH1A1 | |
| SCHEMBL8537283 | 0.80 | LMNA (0.61) | MAPK1LMNATSHRHTTALDH1A1 | |
| SCHEMBL912709 | 0.77 | MAPT (0.54) | SMN1; SMN2CYP1A2MAPK1LMNAHTT | |
| SCHEMBL18383753 | 0.77 | MAPT (0.51) | SMN1; SMN2CYP1A2HTTALDH1A1NPSR1 | |
| SCHEMBL28998051 | 0.77 | ALDH1A1 (0.59) | SMN1; SMN2MAPK1LMNATSHRHTT | |
| SCHEMBL15386251 | 0.77 | MAPT (0.50) | SMN1; SMN2MAPK1HTTALDH1A1NPSR1 | |
| SCHEMBL1310780 | 0.76 | MAPT (0.60) | SMN1; SMN2MAPK1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951040-B2 | 1,3,5 -triazine based PI3K inhibitors as anticancer agents and a process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| EP-0629622-B1 | S-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KK (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5489591-A | INHIBITORS OF AROMATASE; TREATING ENDOMETRIOSIS, BREAST CANCER CYSTIC OVARIES | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-02-06 | — | — | US | disclosed |
| EP-0629622-A1 | s-TRIAZINE DERIVATIVE AND REMEDY FOR ESTROGEN-DEPENDENT DISEASES CONTAINING THE SAME AS ACTIVE INGREDIENT | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1994-12-21 | — | — | EP | disclosed |