Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555410 | 0.82 | P2RX4 (0.49) | P2RX4CA12CA1CA2CA9 | |
| SCHEMBL11553287 | 0.80 | P2RX4 (0.43) | P2RX4CA12CA1CA2CA9 | |
| SCHEMBL11552594 | 0.80 | P2RX4 (0.50) | P2RX4 | |
| SCHEMBL11556382 | 0.78 | CYP2C9 (0.44) | P2RX4ARCA1CA2CA9 | |
| SCHEMBL11555056 | 0.77 | PRKAB2 (0.42) | P2RX4CA12CA1CA2CA9 | |
| SCHEMBL11553517 | 0.77 | P2RX4 (0.53) | P2RX4 | |
| SCHEMBL11552574 | 0.75 | CA1 (0.48) | CA12CA1CA2CA9CA3 | |
| SCHEMBL7090901 | 0.75 | CASP1 (0.52) | CASP1MEN1HPGDKMT2A | |
| SCHEMBL3877578 | 0.75 | CASP1 (0.49) | CA12CA1CA2CA9CASP1 | |
| Ammonia Solution, Strong SCHEMBL7974729 | 0.74 | CASP1 (0.51) | CASP1MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161533-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |