Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529086 | 0.88 | CA2 (0.54) | CA2CA9CA12CA14CA1 | |
| SCHEMBL8741343 | 0.85 | CASP1 (0.51) | CASP1MEN1KMT2ANPC1TSHR | |
| SCHEMBL10864060 | 0.81 | HTR6 (0.49) | CA2CA9CA12CA14CA1 | |
| SCHEMBL5682949 | 0.81 | CASP1 (0.49) | CASP1MEN1KMT2ANPC1TSHR | |
| SCHEMBL7090901 | 0.81 | CASP1 (0.52) | CASP1MEN1KMT2ANPC1TSHR | |
| SCHEMBL19625168 | 0.80 | GLO1 (0.39) | CASP1CA2CA9CA12CA14 | |
| Ammonia Solution, Strong SCHEMBL7974729 | 0.80 | CASP1 (0.51) | CASP1MEN1KMT2ANPC1TSHR | |
| SCHEMBL7187841 | 0.79 | HTR6 (0.64) | CASP1MEN1KMT2ANPC1TSHR | |
| SCHEMBL3877575 | 0.79 | CASP1 (0.51) | CASP1CA2CA9CA12CA14 | |
| SCHEMBL19625128 | 0.78 | TBXA2R (0.62) | CA2CA12SMN1; SMN2CA5ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705000-A | Ailamode intermediate and its synthetic method | 南京红杉生物科技有限公司 | 2019-05-03 | — | — | CN | claimed |
| EP-0074595-B1 | SUBSTITUTED PHENYLSULFONYL UREA DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-23 | — | — | EP | claimed |
| CN-109705000-A | Ailamode intermediate and its synthetic method | 南京红杉生物科技有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109705000-A | Ailamode intermediate and its synthetic method | 南京红杉生物科技有限公司 | 2019-05-03 | — | — | CN | disclosed |
| EP-2089365-A1 | HETEROCYCLIC DERIVED METALLOPROTEASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008045668-A1 | HETEROCYCLIC DERIVED METALLOPROTEASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-04-17 | — | — | WO | disclosed |
| EP-0074595-B1 | SUBSTITUTED PHENYLSULFONYL UREA DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4545944-A | Herbicidally active novel substituted phenylsulfonylurea derivatives and intermediates therefor | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-10-08 | — | — | US | disclosed |
| US-4474600-A | Herbicidally active novel substituted phenylsulfonylurea derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0074595-A1 | Substituted phenylsulfonyl urea derivatives, process and intermediates for their preparation, and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-03-23 | — | — | EP | disclosed |