Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 16/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555056 | 0.88 | PRKAB2 (0.42) | P2RX4KDM4E | |
| SCHEMBL11552594 | 0.88 | P2RX4 (0.50) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL11555410 | 0.85 | P2RX4 (0.49) | P2RX4POLBTMEM97CYP2C8CYP2D6 | |
| SCHEMBL11553287 | 0.81 | P2RX4 (0.43) | P2RX4 | |
| SCHEMBL11552599 | 0.77 | P2RX4 (0.40) | P2RX4 | |
| SCHEMBL11554544 | 0.74 | ALDH1A1 (0.45) | P2RX4KDM4EPOLB | |
| SCHEMBL11555741 | 0.71 | P2RX4 (0.46) | P2RX4TMEM97CYP2C8CYP2D6CYP2C9 | |
| SCHEMBL21800161 | 0.70 | CA2 (0.49) | — | |
| SCHEMBL18700972 | 0.70 | PRKAB2 (0.48) | — | |
| SCHEMBL18700925 | 0.70 | PRKAB2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161533-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |