Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561396 | 0.90 | NT5E (0.41) | MAOBMAOA | |
| SCHEMBL11556384 | 0.90 | FPR1 (0.41) | MAOBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11560670 | 0.89 | CA1 (0.34) | MAPTKDM4EGLAALDH1A1 | |
| SCHEMBL11561098 | 0.89 | ALDH1A1 (0.43) | MAOBNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11559759 | 0.87 | RAB9A (0.42) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11555482 | 0.79 | FPR1 (0.39) | MAOBMAPTRAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11561705 | 0.78 | ALDH1A1 (0.38) | MAOBMAPTNPC1RAB9AKDM4E | |
| SCHEMBL11527471 | 0.69 | LMNA (0.51) | TP53MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11526592 | 0.68 | TP53 (0.43) | TP53RAB9AALDH1A1 | |
| SCHEMBL11562685 | 0.67 | MEN1 (0.39) | MAPTGLAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177273-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | SANDOZ, INC. (US) | 1979-12-04 | — | — | US | disclosed |