Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559669 | 0.83 | ULK1 (0.51) | ULK1HSD17B10ALOX15NPC1RAB9A | |
| SCHEMBL11556220 | 0.78 | PRMT1 (0.48) | ULK1HSD17B10ALOX15NPC1RAB9A | |
| SCHEMBL11559239 | 0.77 | MAPK14 (0.35) | ULK1 | |
| SCHEMBL30269611 | 0.76 | CLK1 (0.53) | ULK1HSD17B10ALOX15NPC1RAB9A | |
| SCHEMBL11557056 | 0.76 | CLK1 (0.53) | ULK1HSD17B10ALOX15NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11554953 | 0.75 | CLK1 (0.52) | ULK1HSD17B10ALOX15NPC1RAB9A | |
| SCHEMBL378949 | 0.73 | SMN1; SMN2 (0.62) | HSD17B10ALOX15NPC1RAB9ALMNA | |
| SCHEMBL14869453 | 0.72 | LMNA (0.62) | ULK1ALOX15NPC1RAB9ALMNA | |
| SCHEMBL29394329 | 0.71 | TDO2 (0.44) | ULK1NPC1RAB9ALMNAKMT2A | |
| SCHEMBL653856 | 0.71 | SYK (0.68) | ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144341-A | ANTIPYRETICS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |