Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA7 | P43166 | 7/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA5A | P35218 | 4/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 4/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553179 | 0.92 | MEN1 (0.45) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL11555834 | 0.88 | CA2 (0.55) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL11553201 | 0.80 | CA2 (0.55) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL11555915 | 0.79 | SLC22A12 (0.52) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL11553233 | 0.79 | STK17B (0.61) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL11554605 | 0.77 | CYP2D6 (0.46) | ALDH1A1RAB9ACA1CA2CA12 | |
| SCHEMBL11552088 | 0.73 | CA12 (0.43) | ALDH1A1SMN1; SMN2CA1CA2CA12 | |
| SCHEMBL941153 | 0.73 | MMP2 (0.54) | CA1CA2CA12CA7CA4 | |
| SCHEMBL21950993 | 0.73 | CA9 (0.59) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL11554044 | 0.73 | MAPT (0.45) | ALDH1A1RAB9ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |