Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.52 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550671 | 0.91 | SLC22A12 (0.64) | SLC22A12EYA3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11552784 | 0.87 | SLC22A12 (0.51) | SLC22A12EYA3CA1CA2CA7 | |
| SCHEMBL11553196 | 0.86 | SLC22A12 (0.50) | SLC22A12EYA3CA1CA2CA7 | |
| SCHEMBL11556111 | 0.83 | CYP2C19 (0.60) | SLC22A12EYA3CA1CA2CA7 | |
| SCHEMBL11550650 | 0.83 | SLC22A12 (0.64) | SLC22A12EYA3CA1CA2CA7 | |
| SCHEMBL11553179 | 0.81 | MEN1 (0.45) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11557225 | 0.79 | ALDH1A1 (0.46) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11552088 | 0.77 | CA12 (0.43) | CA1CA2CA7CA13CA12 | |
| SCHEMBL11552492 | 0.76 | EYA3 (0.52) | SLC22A12EYA3CA1CA2CA7 | |
| SCHEMBL11556805 | 0.74 | STAT3 (0.45) | SLC22A12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |