Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556618 | 0.92 | BCAT1 (0.48) | FBP1CA2CA12CA1CA9 | |
| SCHEMBL11555834 | 0.88 | CA2 (0.55) | CYP2D6CA2CA12CA1CA9 | |
| SCHEMBL11553201 | 0.80 | CA2 (0.55) | CA2CA12CA1CA9L3MBTL1 | |
| SCHEMBL11110472 | 0.78 | HPGD (0.56) | CYP2D6CA2CA12CA1CA9 | |
| SCHEMBL11557225 | 0.77 | ALDH1A1 (0.46) | CA2CA12CA1CA9KDM4E | |
| SCHEMBL28909093 | 0.75 | L3MBTL1 (0.68) | FBP1L3MBTL1ALDH1A1GSTO1 | |
| SCHEMBL5503814 | 0.75 | ALDH1A1 (0.65) | CYP2D6CA2CA12CA1CA9 | |
| SCHEMBL5511361 | 0.75 | LMNA (0.59) | CYP2D6KDM4EALDH1A1RAB9APOLB | |
| SCHEMBL22588068 | 0.73 | CYP2D6 (0.51) | CYP2D6FBP1CA2CA12CA1 | |
| SCHEMBL8267505 | 0.72 | CLK1 (0.61) | CYP2D6KDM4EALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |