Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | AOC1 | P19801 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108556 | 0.89 | IDO1 (0.40) | IDO1TDP1L3MBTL1TRPV1AOC1 | |
| SCHEMBL963410 | 0.84 | IDO1 (0.48) | IDO1TDP1L3MBTL1AOC1AOC3 | |
| SCHEMBL13689141 | 0.82 | ADRA2B (0.42) | IDO1TDP1L3MBTL1AOC1AOC3 | |
| SCHEMBL28218525 | 0.79 | SLC6A2 (0.40) | IDO1TDP1AOC1AOC3 | |
| SCHEMBL29336453 | 0.79 | IDO1 (0.38) | IDO1TDP1L3MBTL1AOC1AOC3 | |
| SCHEMBL25031389 | 0.78 | LIPG (0.47) | POLB | |
| SCHEMBL30316736 | 0.78 | ALDH1A1 (0.46) | IDO1TDP1ALDH1A1POLB | |
| SCHEMBL8097565 | 0.78 | ALDH1A1 (0.46) | IDO1TDP1ALDH1A1POLB | |
| SCHEMBL932125 | 0.78 | TDP1 (0.40) | IDO1TDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL29110680 | 0.77 | HDAC3 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002638-A1 | Addition salts of substituted aralkylamins and therapeutic composition containing them | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1979-06-27 | — | — | EP | disclosed |