Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | AOC1 | P19801 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13689141 | 0.81 | ADRA2B (0.42) | TDP1IDO1AOC1AOC3 | |
| SCHEMBL28108556 | 0.80 | IDO1 (0.40) | TDP1IDO1ADRB2ADRB1AOC1 | |
| SCHEMBL11558262 | 0.79 | IDO1 (0.42) | TDP1IDO1AOC1AOC3 | |
| SCHEMBL21345586 | 0.77 | TAAR1 (0.50) | SLC6A2HTR2ASIGMAR1ADRB2ADRB1 | |
| SCHEMBL25031389 | 0.76 | LIPG (0.47) | HTR2A | |
| SCHEMBL8097565 | 0.76 | ALDH1A1 (0.46) | TDP1SIGMAR1IDO1 | |
| SCHEMBL30316736 | 0.76 | ALDH1A1 (0.46) | TDP1SIGMAR1IDO1 | |
| SCHEMBL4852440 | 0.76 | TAAR1 (0.63) | SLC6A2HTR2ASIGMAR1IDO1ADRB2 | |
| SCHEMBL11155402 | 0.76 | TAAR1 (0.48) | SLC6A2HTR2ASIGMAR1IDO1ADRB2 | |
| SCHEMBL25453155 | 0.76 | MPO (0.56) | CYP2D6HIF1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129409-A | A kind of method of improved synthesis Lamotrigine | 三金集团湖南三金制药有限责任公司 | 2018-06-08 | — | — | CN | claimed |
| CN-108129409-A | A kind of method of improved synthesis Lamotrigine | 三金集团湖南三金制药有限责任公司 | 2018-06-08 | — | — | CN | disclosed |