Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558987 | 0.80 | MMP9 (0.45) | ACEMMP9MMP1MMP3ADAM17 | |
| SCHEMBL32676972 | 0.75 | ACE (0.54) | ACELMNACHEK1JAK2 | |
| SCHEMBL2092090 | 0.75 | ACE (0.54) | ACELMNACHEK1JAK2 | |
| SCHEMBL3154327 | 0.75 | ACE (0.54) | ACELMNACHEK1JAK2 | |
| SCHEMBL13971489 | 0.75 | ACE (0.54) | ACELMNACHEK1JAK2 | |
| SCHEMBL8028671 | 0.74 | ACE (0.36) | ACEMMP9MMP1MMP3ADAM17 | |
| SCHEMBL8383954 | 0.70 | MMP8 (0.57) | MMP9MMP1MMP3SMN1; SMN2 | |
| SCHEMBL2150487 | 0.70 | OPRM1 (0.51) | MMP3CHEK1JAK2 | |
| SCHEMBL12652993 | 0.70 | OPRM1 (0.51) | MMP3CHEK1JAK2 | |
| SCHEMBL11558268 | 0.70 | ACE (0.46) | ACEKMT2ADRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147787-A | ANTICOAGULANTS | PARCOR (FR) | 1979-04-03 | — | — | US | disclosed |