Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.53 |
| ▸ | EYA3 | Q99504 | 3/20 | 0.53 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11553624 | 0.91 | CYP2C19 (0.53) | CYP2C19EYA3BCAT1CYP2C9LMNA | |
| SCHEMBL11555043 | 0.87 | CYP2C19 (0.56) | CYP2C19EYA3BCAT1CYP2C9LMNA | |
| SCHEMBL11556449 | 0.86 | EYA3 (0.58) | CYP2C19EYA3CYP2C9LMNAHTT | |
| SCHEMBL11555688 | 0.78 | CYP2C19 (0.60) | CYP2C19EYA3CYP2C9LMNAHTT | |
| SCHEMBL11554551 | 0.77 | CYP2C19 (0.57) | CYP2C19EYA3BCAT1CYP2C9LMNA | |
| SCHEMBL11555575 | 0.75 | CYP2C19 (0.62) | CYP2C19EYA3CYP2C9LMNAHTT | |
| SCHEMBL11554930 | 0.74 | VCAM1 (0.59) | CYP2C19EYA3LMNAHTTPOLB | |
| SCHEMBL11552492 | 0.73 | EYA3 (0.52) | CYP2C19EYA3CYP2C9LMNATHRB | |
| SCHEMBL11551818 | 0.72 | EYA3 (0.55) | CYP2C19EYA3CYP2C9LMNAHTT | |
| SCHEMBL11556111 | 0.72 | CYP2C19 (0.60) | CYP2C19EYA3CYP2C9LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |