Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749704 | 0.74 | SQOR (0.42) | — | |
| SCHEMBL9469935 | 0.73 | TLR8 (0.47) | TLR8 | |
| SCHEMBL14825920 | 0.73 | L3MBTL1 (0.46) | HCAR3 | |
| SCHEMBL8452074 | 0.72 | KMT2A (0.40) | TLR8 | |
| SCHEMBL7812124 | 0.70 | TLR8 (0.41) | TLR8 | |
| SCHEMBL2078386 | 0.70 | TSHR (0.51) | — | |
| SCHEMBL3173105 | 0.70 | TSHR (0.44) | — | |
| SCHEMBL5175759 | 0.69 | SLC9A1 (0.37) | TLR8 | |
| SCHEMBL9631796 | 0.69 | SLC9A1 (0.39) | TLR8 | |
| SCHEMBL9631798 | 0.69 | SLC9A1 (0.39) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154841-A | Antiinflammatory 1-acyl-3(5)-alkyl-5(3)-phenyl-1,2,4-triazoles | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |