Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812124 | 0.87 | TLR8 (0.41) | SLC9A1MEN1CYP1A2CYP2C9CRHBP | |
| SCHEMBL5319171 | 0.84 | TSHR (0.40) | MGLL | |
| SCHEMBL11434230 | 0.81 | ALDH1A1 (0.33) | CYP1A2CYP2C9CYP2C19TLR7PI4KA | |
| SCHEMBL15942755 | 0.79 | GABRA1 (0.34) | SLC9A1 | |
| SCHEMBL5320970 | 0.78 | TSHR (0.37) | MGLL | |
| SCHEMBL9631796 | 0.78 | SLC9A1 (0.39) | SLC9A1KMT2ATLR8KDRMGLL | |
| SCHEMBL8452074 | 0.77 | KMT2A (0.40) | SLC9A1MEN1CYP1A2CYP2C9CRHBP | |
| SCHEMBL20809055 | 0.75 | ADORA2A (0.35) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL9631798 | 0.74 | SLC9A1 (0.39) | SLC9A1TLR8KDRMGLL | |
| SCHEMBL11202892 | 0.74 | PTGS2 (0.36) | TLR7PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017125-A1 | CB1 ANTAGONISTS OR INVERSE ANTAGONISTS AS THERAPEUTICAL AGENTS FOR THE TREATMENT OF INFLAMMATION INVOLVING GENE EXPRESSION | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-15 | — | — | WO | claimed |
| EP-1752149-A1 | CB1 Antagonists or inverse agonists as therapeutical agents for the treatment of inflammation involving gene expression | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-14 | — | — | EP | claimed |
| WO-2007017125-A1 | CB1 ANTAGONISTS OR INVERSE ANTAGONISTS AS THERAPEUTICAL AGENTS FOR THE TREATMENT OF INFLAMMATION INVOLVING GENE EXPRESSION | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |
| EP-1752149-A1 | CB1 Antagonists or inverse agonists as therapeutical agents for the treatment of inflammation involving gene expression | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-14 | — | — | EP | disclosed |