Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554281 | 0.89 | KDR (0.38) | LMNAMAPTKDM4EMEN1KMT2A | |
| SCHEMBL11559423 | 0.83 | GRM5 (0.51) | GRM5CSNK2A1P2RX1TMPRSS4LMNA | |
| SCHEMBL11564423 | 0.78 | KDR (0.49) | GRM5LMNAMAPTKDM4EMEN1 | |
| SCHEMBL11562452 | 0.75 | ALDH1A1 (0.38) | P2RX1LMNAMAPTKDM4EKMT2A | |
| SCHEMBL10877859 | 0.71 | NPC1 (0.40) | GRM5MAPTHTTPLAUF2 | |
| SCHEMBL11761064 | 0.69 | CYP1A2 (0.56) | GRM5MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11562472 | 0.69 | P2RX1 (0.46) | P2RX1TMPRSS4LMNAKDM4EMEN1 | |
| SCHEMBL11105640 | 0.68 | KDM4E (0.60) | LMNAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10880124 | 0.68 | ALDH1A1 (0.48) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11562495 | 0.68 | HSP90AA1 (0.38) | GRM5P2RX1TMPRSS4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | claimed |
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |