Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 3/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559697 | 0.89 | GRM5 (0.39) | F2F10PLAUPLATNPC1 | |
| SCHEMBL11564423 | 0.86 | KDR (0.49) | KDRPLGKLK1KLK6F2 | |
| SCHEMBL11562452 | 0.75 | ALDH1A1 (0.38) | KDRPLGKLK1F2F10 | |
| SCHEMBL11559423 | 0.75 | GRM5 (0.51) | KDRF2F10PLAUPLAT | |
| SCHEMBL11565071 | 0.71 | ALDH1A1 (0.49) | RAB9AALOX15LMNAMAPTHTT | |
| SCHEMBL11557569 | 0.69 | PNLIP (0.40) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11564078 | 0.69 | P2RX1 (0.48) | PLGF2F10PLAUPLAT | |
| SCHEMBL11559729 | 0.69 | KLKB1 (0.51) | NPC1RAB9ATAS1R3TAS1R1ALOX15 | |
| SCHEMBL11556748 | 0.69 | SMN1; SMN2 (0.51) | PLGKLK1KLK6NPC1RAB9A | |
| SCHEMBL11554274 | 0.69 | SMN1; SMN2 (0.43) | NPC1RAB9AALOX15LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |