Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559491 | 0.83 | KDR (0.51) | ALDH1A1KDM4EHSD17B10HPGDKDR | |
| SCHEMBL11559697 | 0.75 | GRM5 (0.39) | ALDH1A1KDM4EHSD17B10HPGDNPC1 | |
| SCHEMBL11554281 | 0.75 | KDR (0.38) | ALDH1A1KDM4EHPGDKDRNPC1 | |
| SCHEMBL2662445 | 0.72 | ALPL (0.61) | ALDH1A1KDM4EHPGDNPC1RAB9A | |
| SCHEMBL10880639 | 0.71 | ALPL (0.46) | ALDH1A1KDM4EHSD17B10HPGDKDR | |
| SCHEMBL11557699 | 0.69 | TERT (0.40) | ALDH1A1KDM4EHPGDKDRNPC1 | |
| SCHEMBL11105640 | 0.68 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10HPGDNPC1 | |
| SCHEMBL10877660 | 0.68 | HPGD (0.58) | ALDH1A1HPGDRAB9AMAPTKMT2A | |
| SCHEMBL11557497 | 0.67 | BRD4 (0.38) | ALDH1A1KDM4EKDRNPC1RAB9A | |
| SCHEMBL11562445 | 0.67 | RAB9A (0.45) | ALDH1A1HSD17B10HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146631-A | ANTIALLERGENS, RESPIRATORY DISORDERS | MAY & BAKER LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |