SCHEMBL11559809

SCHEMBL11559809

FC(F)(F)C(F)(F)Cc1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.57
CYP1A2 P05177 3/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 1/20 0.51
HIF1A Q16665 1/20 0.51
BTN3A1 O00481 1/20 0.50
PDE3A Q14432 1/20 0.50
CYP2D6 P10635 1/20 0.48
CHRNA7 P36544 1/20 0.47
CHRNB2 P17787 2/20 0.46
CHRNA4 P43681 2/20 0.46
CYP2A6 P11509 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
KCNA5 P22460 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95744 0.83 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL29582746 0.83 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2375127 0.80 FDPS (0.57) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11231844 0.79 FDPS (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11240731 0.77 FDPS (0.59) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL14036231 0.76 CYP1A2 (0.61) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL74145 0.75 CYP1A2 (0.55) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL31358573 0.75 CYP1A2 (0.55) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2482123 0.74 FDPS (0.64) FDPSCYP1A2CYP3A4CYP2C9CYP2C19
Ammonia Solution, Strong SCHEMBL27962089 0.73 CHRNB2 (0.57) FDPSCYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172946-A Method for manufacture of fluoroalkyl pyridines AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1979-10-30 US disclosed