Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135182 | 0.91 | KMT2A (0.41) | KMT2AGAAHSD17B10POLBTDP1 | |
| Hydrochloric Acid SCHEMBL11559023 | 0.90 | KMT2A (0.40) | KMT2AGAAHSD17B10POLBTDP1 | |
| SCHEMBL11053104 | 0.86 | ABL1 (0.32) | KMT2AGAAHSD17B10TDP1ALDH1A1 | |
| SCHEMBL11056263 | 0.85 | ALDH1A1 (0.39) | KMT2AGAAHSD17B10ALDH1A1HPGD | |
| SCHEMBL11061778 | 0.85 | ALDH1A1 (0.38) | KMT2AGAAHSD17B10POLBTDP1 | |
| SCHEMBL11057304 | 0.84 | L3MBTL1 (0.38) | KMT2ATDP1ALDH1A1HPGDMAPT | |
| SCHEMBL11053093 | 0.84 | PTGES (0.36) | KMT2AALDH1A1MEN1LMNAHTT | |
| SCHEMBL11054132 | 0.83 | CA1 (0.34) | TDP1MAPTF2RAB9A | |
| SCHEMBL11055145 | 0.82 | KMT2A (0.40) | KMT2AGAAHSD17B10POLBTDP1 | |
| SCHEMBL11058223 | 0.82 | ALOX5 (0.39) | GAAALDH1A1HPGDRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |