Sugi Predict

Sugi Predict / Compounds / SCHEMBL1476483

SCHEMBL1476483

SCHEMBL1476483

NOC(N)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES1 P23141 4/20 0.56
▸ SRC P12931 1/20 0.43
▸ TSHR P16473 3/20 0.41
▸ MAPT P10636 3/20 0.41
▸ POLB P06746 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ PARP1 P09874 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ RECQL P46063 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ PMP22 Q01453 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ TDP1 Q9NUW8 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ CYP1A2 P05177 2/20 0.40
▸ F2 P00734 1/20 0.40
▸ LMNA P02545 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ KMT2A Q03164 2/20 0.39
▸ KCNN4 O15554 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL4779742 0.94 CES1 (0.56) CES1SRCTSHRMAPTPOLB
SCHEMBL16280591 0.78 CES1 (0.50) CES1SRCTSHRMAPTPOLB
SCHEMBL1395205 0.77 CES1 (0.53) CES1SRCTSHRMAPTPOLB
SCHEMBL1878464 0.77 CES1 (0.52) CES1SRCTSHRMAPTPOLB
SCHEMBL461653 0.75 CES1 (0.50) CES1SRCTSHRMAPTPOLB
SCHEMBL10887738 0.73 CES1 (0.53) CES1SRCTSHRMAPTPOLB
SCHEMBL4719207 0.73 CES1 (0.48) CES1SRCTSHRMAPTPOLB
SCHEMBL669434 0.73 CES1 (0.58) CES1SRCTSHRMAPTPOLB
SCHEMBL1127623 0.72 CES1 (0.57) CES1SRCTSHRMAPTPOLB
SCHEMBL15173 0.72 CES1 (1.00) CES1SRCTSHRMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107286303-B A kind of aqueous polyurethane acrylate lotion and its aqueous ink used for plastic of preparation 中山大学 2019-05-31 — — CN claimed
CN-107286303-A A kind of aqueous polyurethane acrylate emulsion and its aqueous ink used for plastic of preparation 中山大学 2017-10-24 — — CN claimed
WO-2023105480-A1 POLYETHERIMIDE HAVING REACTIVE BRANCHING SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-06-15 — — WO disclosed
US-20210280861-A1 NEGATIVE ELECTRODE AND METHOD FOR PRODUCING NEGATIVE ELECTRODE, AND ELECTRODE BINDING AGENT KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2021-09-09 — — US disclosed
CN-109537299-A A kind of waterborne polyurethane coating agent and preparation method thereof 广西南宁桂尔创环保科技有限公司 2019-03-29 — — CN disclosed
CN-109504269-A A kind of polyurethane building coating and preparation method thereof 广西南宁桂尔创环保科技有限公司 2019-03-22 — — CN disclosed
CN-105873665-B Composite polyamide membrane post-treated with nitrous acid 陶氏环球技术有限责任公司 2019-01-01 — — CN disclosed
CN-107540806-A Polyurethane type high molecular ultraviolet absorbent 台湾永光化学工业股份有限公司 2018-01-05 — — CN disclosed
US-9688606-B2 Process for acidic scrubbing of dinitrotoluene in the presence of hydrocyanic acid BASF SE (DE) 2017-06-27 — — US disclosed
CN-104893539-B Preparation method of hydrophobic and flame-retardant PU (polyurethane) coating 西安科技大学 2017-04-19 — — CN disclosed
US-20160251302-A1 PROCESS FOR ACIDIC SCRUBBING OF DINITROTOLUENE IN THE PRESENCE OF HYDROCYANIC ACID BASF SE (DE) 2016-09-01 — — US disclosed
CN-1326963-C Release coating containing thermoplastic silicone-containing polymer 3M INNOVATIVE PROPERTIES CO (US) 2007-07-18 — — CN disclosed
US-20060246450-A1 Ligational encoding of small molecules NUEVOLUTION A/S (DK) 2006-11-02 — — US disclosed
WO-2006004791-A1 ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-01-12 — — WO disclosed
CN-1653148-A Release coating containing thermoplastic silicone-containing polymer 3M INNOVATIVE PROPERTIES CO (US) 2005-08-10 — — CN disclosed
US-6855713-B2 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-02-15 — — US disclosed
CN-1495218-A Anti-bacterial high molecule and its preparation method, anti-bacterial high-molecule covering film and its preparation method and product with said surface covering film ���׿ƹɷ����޹�˾ 2004-05-12 — — CN disclosed
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-10 — — US disclosed
US-6316623-B1 USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS ISIS PHARMACEUTICALS, INC. 2001-11-13 — — US disclosed
US-5281690-A Multilayer element with polymer layers BREWER SCIENCE, INC. (US) 1994-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246450-A1 Ligational encoding of small molecules POLI, PCNA, LIG4 CES1 4587/4885SRC 2564/4885TSHR 3656/4885
US-20030130265-A1 Benzimidazole derivatives, a process for their manufacture and use as a medicine TPSAB1, PRSS3, TPSD1 CES1 41/4885SRC 3751/4885TSHR 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.