Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101775 | 0.84 | CES1 (0.53) | CES1SRCMAPTTSHRPOLB | |
| SCHEMBL621110 | 0.82 | CES1 (0.52) | CES1SRCMAPTTSHRPOLB | |
| SCHEMBL277653 | 0.81 | CES1 (0.65) | CES1SRCMAPTTSHRCYP2C19 | |
| Methoxymethane SCHEMBL36163 | 0.79 | CES1 (0.62) | CES1SRCMAPTTSHRCYP2C19 | |
| SCHEMBL459656 | 0.79 | CES1 (0.49) | CES1SRCMAPTTSHRTDP1 | |
| SCHEMBL11072129 | 0.79 | CES1 (0.53) | CES1SRCMAPTTSHRHSD17B10 | |
| SCHEMBL8592886 | 0.78 | KCNN4 (0.42) | CES1SRCMAPTCYP2C19KMT2A | |
| SCHEMBL1476483 | 0.78 | CES1 (0.56) | CES1SRCMAPTTSHRPOLB | |
| SCHEMBL173918 | 0.78 | CES1 (0.51) | CES1SRCMAPTTSHRCYP3A4 | |
| SCHEMBL6528610 | 0.78 | CES1 (0.47) | CES1SRCMAPTTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9587259-B2 | Escherichia coli capable of producing 3-amino-4-hydroxybenzoic acid | AJINOMOTO CO., INC. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9587259-B2 | Escherichia coli capable of producing 3-amino-4-hydroxybenzoic acid | AJINOMOTO CO., INC. (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9447443-B2 | Method for producing 3-acetylamino-4-hydroxybenzoic acid | AJINOMOTO CO., INC. (JP) | 2016-09-20 | — | — | US | disclosed |
| EP-2857510-A1 | METHOD FOR PRODUCING 3-ACETYLAMINO-4-HYDROXYBENZOIC ACID | Ajinomoto Co., Inc. (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-20150079644-A1 | Method for Producing 3-Acetylamino-4-Hydroxybenzoic Acid | AJINOMOTO CO., INC. (JP) | 2015-03-19 | — | — | US | disclosed |
| EP-2821479-A1 | ESCHERICHIA COLI CAPABLE OF PRODUCING 3-AMINO-4-HYDROXYBENZOIC ACID | Ajinomoto Co., Inc. (JP) | 2015-01-07 | — | — | EP | disclosed |
| EP-2821479-A1 | ESCHERICHIA COLI CAPABLE OF PRODUCING 3-AMINO-4-HYDROXYBENZOIC ACID | Ajinomoto Co., Inc. (JP) | 2015-01-07 | — | — | EP | disclosed |
| US-20140364579-A1 | Escherichia coli Capable of Producing 3-Amino-4-Hydroxybenzoic Acid | AJINOMOTO CO., INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140364579-A1 | Escherichia coli Capable of Producing 3-Amino-4-Hydroxybenzoic Acid | AJINOMOTO CO., INC. (JP) | 2014-12-11 | — | — | US | disclosed |