Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 8/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568138 | 0.85 | MRGPRX4 (0.49) | BRAFKDRMAPTNPSR1 | |
| SCHEMBL11567998 | 0.85 | STK39 (0.45) | BRAFKDRSTK39PARGPNLIP | |
| SCHEMBL11564073 | 0.79 | RXRA (0.48) | BRAFKDRMAPTNPSR1 | |
| SCHEMBL11050028 | 0.79 | BRAF (0.46) | BRAFKDRMAPTNPSR1 | |
| SCHEMBL11565226 | 0.76 | BRAF (0.47) | BRAFKDRMAPTNPSR1SCN8A | |
| SCHEMBL11563745 | 0.76 | BRAF (0.44) | BRAFKDRMAPTNPSR1 | |
| SCHEMBL11565893 | 0.76 | BRAF (0.46) | BRAFKDRRAF1MAPTNPSR1 | |
| SCHEMBL11566813 | 0.76 | BRAF (0.46) | BRAFKDRRAF1MAPTNPSR1 | |
| SCHEMBL11561946 | 0.75 | RXRA (0.48) | BRAFKDRMAPTNPSR1 | |
| SCHEMBL18205875 | 0.75 | L3MBTL1 (0.52) | MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |