Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 11/20 | 0.46 |
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA7 | P43166 | 5/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA6 | P23280 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555382 | 0.88 | CNR2 (0.56) | CNR2CNR1MMP2CA1CA2 | |
| SCHEMBL11560887 | 0.87 | CNR2 (0.53) | CNR2CNR1MAPT | |
| SCHEMBL11555852 | 0.85 | MMP2 (0.49) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11556393 | 0.83 | MMP2 (0.46) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11556682 | 0.82 | CA1 (0.46) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11555267 | 0.80 | MMP2 (0.48) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL20306409 | 0.77 | CNR2 (0.60) | CNR2CNR1POLBMAPT | |
| SCHEMBL11552311 | 0.76 | MAPT (0.53) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11556111 | 0.76 | CYP2C19 (0.60) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL11554539 | 0.74 | MMP2 (0.50) | CNR2MMP2CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |