Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.56 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560954 | 0.88 | CNR2 (0.55) | CNR2CNR1MMP2POLBMAPT | |
| SCHEMBL11553411 | 0.85 | CNR2 (0.40) | CNR2CNR1MAOAMAOBGABRA1 | |
| SCHEMBL11560887 | 0.77 | CNR2 (0.53) | CNR2CNR1MAPK1MEN1LMNA | |
| SCHEMBL11559523 | 0.75 | CYP2C19 (0.64) | ESR1MAPK1PTGS1EYA2MEN1 | |
| SCHEMBL9444750 | 0.75 | CNR2 (0.73) | CNR2CNR1MAOBESR1ESR2 | |
| SCHEMBL11555852 | 0.72 | MMP2 (0.49) | MMP2POLBMAPTCA1CA2 | |
| SCHEMBL11558589 | 0.71 | ALDH1A1 (0.47) | CNR2CNR1MMP2MAPK1MEN1 | |
| SCHEMBL11556393 | 0.71 | MMP2 (0.46) | MAOBGABRA1GABRA5MMP2POLB | |
| SCHEMBL20306409 | 0.71 | CNR2 (0.60) | CNR2CNR1MAOAMAOBESR1 | |
| SCHEMBL11552685 | 0.71 | NR4A2 (0.46) | PTGS1PTGS2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |