Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560954 | 0.87 | CNR2 (0.55) | CNR2CNR1MAPT | |
| SCHEMBL11554622 | 0.86 | GSTO1 (0.41) | CNR2CNR1GSTO1HTTMAPT | |
| SCHEMBL11554724 | 0.81 | PRNP (0.45) | GSTO1HTTSMN1; SMN2MAPTACLY | |
| SCHEMBL11555382 | 0.77 | CNR2 (0.56) | CNR2CNR1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL11554551 | 0.77 | CYP2C19 (0.57) | MAPTCYP1A2TSHRCYP2C19KMT2A | |
| SCHEMBL20306409 | 0.76 | CNR2 (0.60) | CNR2CNR1MAPTCYP1A2TSHR | |
| SCHEMBL11551809 | 0.76 | TDP1 (0.43) | CNR2GSTO1HTTSMN1; SMN2MAPT | |
| SCHEMBL11552566 | 0.73 | KDM4E (0.44) | GSTO1HTTSMN1; SMN2MAPTACLY | |
| SCHEMBL11559300 | 0.73 | RORC (0.43) | CNR2CNR1GSTO1SMN1; SMN2MAPT | |
| SCHEMBL11553624 | 0.73 | CYP2C19 (0.53) | GSTO1HTTMAPTCYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |