Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.60 |
| ▸ | CNR1 | P21554 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444750 | 0.81 | CNR2 (0.73) | CNR2CNR1MAOBCYP2C19CYP2C9 | |
| SCHEMBL11560954 | 0.77 | CNR2 (0.55) | CNR2CNR1POLBMAPT | |
| SCHEMBL11560887 | 0.76 | CNR2 (0.53) | CNR2CNR1CYP2C19MEN1LMNA | |
| SCHEMBL31078701 | 0.71 | CNR2 (0.49) | CNR2CNR1MAOBMEN1LMNA | |
| SCHEMBL1287534 | 0.71 | CYP2C19 (0.74) | CYP2C19CYP2C9MEN1ABCB11LMNA | |
| SCHEMBL11555382 | 0.71 | CNR2 (0.56) | CNR2CNR1MAOBMAOAGABRA1 | |
| SCHEMBL6335286 | 0.69 | PTPN1 (0.60) | CNR2MAOBMAOACYP2C19CYP2C9 | |
| SCHEMBL11959206 | 0.68 | LOXL2 (0.69) | CNR2CNR1CD274CYP2C19CYP2C9 | |
| SCHEMBL10893926 | 0.66 | TTR (0.59) | CNR2CNR1GABRA1MEN1LMNA | |
| SCHEMBL27331479 | 0.66 | CNR2 (0.51) | CNR2CNR1CD274LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005750-B2 | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action | J-PHARMA CO., LTD. (JP) | 2018-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005750-B2 | Developing potent urate transporter inhibitors: compounds designed for their uricosuric action | SLCO2B1, SLCO2A1, SLC10A6 | CNR2 143/4885CNR1 122/4885MAOB 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.