Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836002 | 0.87 | MEN1 (0.36) | ALDH1A1KDM4EKMT2AGAAHPGD | |
| SCHEMBL11564129 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4EKMT2ALMNAKCNK3 | |
| SCHEMBL3633908 | 0.82 | BRD4 (0.46) | ALDH1A1KDM4EKMT2ALMNACYP2C19 | |
| SCHEMBL12718645 | 0.75 | BRD4 (0.39) | LMNAPOLBMAPT | |
| SCHEMBL14920868 | 0.74 | OPRM1 (0.37) | ALDH1A1KMT2ALMNAPOLBMEN1 | |
| SCHEMBL9781696 | 0.74 | CYP3A4 (0.45) | ALDH1A1KDM4EKMT2AMTNR1AMTNR1B | |
| SCHEMBL7822746 | 0.74 | L3MBTL1 (0.38) | KMT2AMEN1 | |
| SCHEMBL30840609 | 0.74 | APP (0.41) | ALDH1A1KMT2ALMNAMEN1MAPT | |
| SCHEMBL10924592 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EKMT2ALMNAKCNK3 | |
| SCHEMBL30267475 | 0.73 | OPRM1 (0.40) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152527-A | 15-Substituted-ω-pentanorprostaglandins | PFIZER INC. (US) | 1979-05-01 | — | — | US | disclosed |