Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16836056 | 0.86 | OPRM1 (0.39) | KDM4EKMT2AGAAHPGDMEN1 | |
| SCHEMBL11561345 | 0.84 | CYP3A4 (0.46) | ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11563271 | 0.83 | ALDH1A1 (0.42) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL3309675 | 0.80 | BRD4 (0.50) | LMNAALDH1A1KMT2AGAAHPGD | |
| SCHEMBL10924592 | 0.78 | KDM4E (0.43) | KDM4ELMNAALDH1A1KMT2AKCNK3 | |
| SCHEMBL11358343 | 0.77 | ACHE (0.43) | LMNAALDH1A1KMT2AGAAHPGD | |
| SCHEMBL12718645 | 0.76 | BRD4 (0.39) | LMNAPOLBMAPTSLC22A1SLC6A4 | |
| SCHEMBL4288622 | 0.75 | POLB (0.42) | KDM4ELMNAALDH1A1KMT2AGAA | |
| SCHEMBL9781696 | 0.75 | CYP3A4 (0.45) | KDM4EALDH1A1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL7828042 | 0.74 | KDM4E (0.41) | KDM4ELMNAALDH1A1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152527-A | 15-Substituted-ω-pentanorprostaglandins | PFIZER INC. (US) | 1979-05-01 | — | — | US | disclosed |