Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | G6PD | P11413 | 1/20 | 0.60 |
| ▸ | GALK1 | P51570 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563706 | 0.82 | CA1 (0.47) | MAPTRAB9APOLBKMT2ATP53 | |
| SCHEMBL11561420 | 0.73 | CA2 (0.51) | KMT2AMEN1THRB | |
| SCHEMBL11562150 | 0.71 | CA1 (0.53) | MAPTPOLBKMT2ARXFP1MEN1 | |
| SCHEMBL13411701 | 0.70 | ALDH1A1 (0.49) | RAB9APOLBKMT2ATP53GAA | |
| SCHEMBL11666192 | 0.69 | CA1 (0.47) | KMT2AMEN1THRB | |
| SCHEMBL11821585 | 0.69 | CA1 (0.54) | KMT2AGAAMEN1THRB | |
| SCHEMBL11559048 | 0.67 | MAPT (0.52) | MAPTPOLBKMT2ATP53RXFP1 | |
| SCHEMBL22118520 | 0.66 | CA1 (1.00) | POLB | |
| SCHEMBL11815501 | 0.66 | CA1 (0.50) | MAPTKMT2AMEN1THRB | |
| SCHEMBL11558636 | 0.66 | MAPT (0.50) | MAPTPOLBKMT2ATP53RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042372-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-3972706-A | SUBSTITUTED THIADIAZOL-2-YL-UREAS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |