SCHEMBL115638

SCHEMBL115638

COc1ccc2c(c1)CCCC2=O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 12/20 0.58
MAOB P27338 12/20 0.58
PRKCI P41743 1/20 0.56
HSD17B1 P14061 1/20 0.55
KDM4E B2RXH2 1/20 0.53
HTT P42858 1/20 0.53
METAP1 P53582 1/20 0.51
CYP19A1 P11511 2/20 0.51
CYP11B2 P19099 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29756894 0.96 MAOA (0.58) MAOAMAOBPRKCIHSD17B1KDM4E
SCHEMBL1495967 0.96 MAOA (0.58) MAOAMAOBPRKCIHSD17B1KDM4E
Sulfuric Acid SCHEMBL28143763 0.94 MAOA (0.54) MAOAMAOBPRKCIHSD17B1KDM4E
SCHEMBL7510392 0.91 METAP1 (0.54) MAOAMAOBHSD17B1KDM4EHTT
SCHEMBL268592 0.89 KDM4E (0.56) MAOBKDM4EHTTMETAP1CYP19A1
SCHEMBL27323916 0.88 MAOA (0.51) MAOAMAOBKDM4EHTTMETAP1
Water SCHEMBL28454486 0.87 KDM4E (0.54) MAOBKDM4EHTTMETAP1CYP19A1
Di(Hydroxyethyl)Ether SCHEMBL28140046 0.87 MAOB (0.51) MAOAMAOBPRKCIHSD17B1
SCHEMBL3010868 0.87 HSD17B1 (0.65) MAOAMAOBPRKCIHSD17B1HTT
SCHEMBL120284 0.86 MAOB (0.58) MAOAMAOBKDM4EHTTMETAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2180 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080770-B Fluorescent probe for detecting natural water eutrophication and preparation method and application thereof 云南大学 2025-05-13 CN claimed
CN-119080770-A Fluorescent probe for detecting natural water eutrophication and preparation method and application thereof 云南大学 2024-12-06 CN claimed
CN-115108928-B Nitrogen mustard-tetralone derivative, preparation method and application thereof 广东海洋大学 2024-06-11 CN claimed
CN-117088765-B Method for preparing 6-methoxy-1-tetralone by utilizing microchannel reactor 烟台舜康生物科技有限公司 2023-12-22 CN claimed
CN-117088765-A Method for preparing 6-methoxy-1-tetralone by utilizing microchannel reactor 烟台舜康生物科技有限公司 2023-11-21 CN claimed
CN-116730810-A Synthesis method of medical intermediate 6-methoxy-1-tetralone 上海常丰生物医药科技有限公司 2023-09-12 CN claimed
CN-116554212-A For visually detecting ONOO ‒ Fluorescent probe of (2), preparation method and application 河南大学 2023-08-08 CN claimed
CN-114249352-B Method for treating wastewater generated in production of 6-methoxy tetralone 沈阳化工研究院有限公司 2023-07-28 CN claimed
CN-111333494-B Synthesis method of 6-methoxy-1-tetralone 武汉海昕药物研究有限公司 2023-07-11 CN claimed
CN-113527346-B Fluorescent probe based on BODIPY dye specific response hypochlorous acid, preparation and application 河南大学 2023-06-02 CN claimed
US-4785131-A Substituted cyanonaphthalene process ETHYL CORPORATION (US) 1988-11-15 US claimed
EP-0199646-A2 Process for preparing 6-alkoxy-5-trifluoromethyl-1-naphtoic acids and novel 1-cyano-naphtalene intermediates ETHYL CORPORATION (US) 1986-10-29 EP claimed
US-4603221-A 6-ALKOXYTETRALIN, TRANSITION METAL SALT, TERTIARY AMINE, AMMONIUM OR ALKALI METAL PERSULFATE, OXIDATION ETHYL CORPORATION (US) 1986-07-29 US claimed
EP-0183249-A2 Process for preparing alpha-arylacrylonitriles ETHYL CORPORATION (US) 1986-06-04 EP claimed
US-4590010-A Substituted naphthoic acid process ETHYL CORPORATION (US) 1986-05-20 US claimed
US-4590012-A Process for preparing alpha-arylacrylonitriles ETHYL CORPORATION (US) 1986-05-20 US claimed
US-4590013-A Process for preparing alpha arylacrylonitriles ETHYL CORPORATION (US) 1986-05-20 US claimed
US-4581176-A Process for preparing alpha-arylacrylonitriles ETHYL CORPORATION (US) 1986-04-08 US claimed
US-4536343-A Process for preparing alpha-arylacrylonitriles ETHYL CORPORATION (US) 1985-08-20 US claimed
US-3962291-A TOTAL SYNTHESIS OF 11-ALKYL STEROIDS G. D. SEARLE & CO. (US) 1976-06-08 US claimed