Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568180 | 0.81 | MAPK1 (0.57) | CA1CA2KDM4ECYP2C9ALDH1A1 | |
| SCHEMBL8752341 | 0.80 | CA12 (0.55) | CA1CA2KDM4ECYP2C9THRB | |
| SCHEMBL11777344 | 0.79 | CA1 (0.54) | CA1CA2KDM4ECYP2C9THRB | |
| SCHEMBL18018242 | 0.77 | KDM4E (0.62) | CA1CA2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28774097 | 0.77 | CA1 (0.49) | CA1CA2KDM4ECYP2C9THRB | |
| SCHEMBL7355901 | 0.75 | KDM4E (0.50) | CA1CA2KDM4ECYP2C9THRB | |
| SCHEMBL1772596 | 0.72 | CYP2C9 (0.64) | KDM4ECYP2C9ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL8802227 | 0.70 | KDM4E (0.59) | CA1CA2KDM4ECYP2C9THRB | |
| Xanthone SCHEMBL5341136 | 0.69 | MAOA (0.82) | KDM4EALDH1A1CYP3A4HSD17B10MAOA | |
| SCHEMBL19679786 | 0.67 | NPC1 (0.63) | CA1CA2KDM4ETHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |