SCHEMBL19679786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28245008	0.79	CYP2C19 (0.79)	NPC1MAPTKMT2ACYP2C19EYA3
	SCHEMBL5562068	0.79	MAPT (0.58)	NPC1MAPTKMT2ACYP2C19EYA3
	SCHEMBL429754	0.77	MAPT (1.00)	NPC1MAPTKMT2ACYP2C19PTPN1
	SCHEMBL7068281	0.77	L3MBTL1 (0.67)	NPC1MAPTKMT2ACYP2C19EYA3
	SCHEMBL32673238	0.77	MAPT (0.45)	NPC1MAPTKMT2ACYP2C19PTPN1
	SCHEMBL18018242	0.76	KDM4E (0.62)	NPC1MAPTKMT2ACYP2C19SMN1; SMN2
	SCHEMBL1287913	0.75	EYA3 (0.81)	MAPTKMT2ACYP2C19EYA3PTPN1
	Xanthone SCHEMBL9762833	0.74	MAOA (0.69)	NPC1MAPTKMT2ASMN1; SMN2RAB9A
	SCHEMBL11777344	0.74	CA1 (0.54)	MAPTSMN1; SMN2ALDH1A1KDM4ETHRB
	SCHEMBL11734971	0.73	EYA3 (0.57)	NPC1MAPTKMT2ACYP2C19EYA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.