Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11777344 | 0.85 | CA1 (0.54) | CA1CA2KDM4ETHRBMAOA | |
| SCHEMBL28774097 | 0.83 | CA1 (0.49) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL15346066 | 0.81 | CYP2C9 (0.66) | CA12CA9KDM4ENPC1RAB9A | |
| SCHEMBL7355901 | 0.81 | KDM4E (0.50) | CA1CA2KDM4ETHRBMAOA | |
| SCHEMBL11564159 | 0.80 | CA1 (0.49) | CA12CA9CA1CA2KDM4E | |
| SCHEMBL311250 | 0.78 | KDM4E (0.62) | CA12CA9CA1CA2KDM4E | |
| Xanthone SCHEMBL27726954 | 0.76 | MAOA (0.78) | CA12CA9KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28525823 | 0.75 | CA12 (0.62) | CA12CA9KDM4EALDH1A1MAPT | |
| SCHEMBL8802227 | 0.75 | KDM4E (0.59) | CA12CA9CA1CA2KDM4E | |
| Xanthone SCHEMBL18138444 | 0.74 | MAOA (0.75) | CA12CA9CA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561830-B1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1997-04-16 | — | — | EP | claimed |
| EP-0561830-A1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES. | BASF AG (DE) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010489-A1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| EP-0561830-B1 | 2-AMINO-4-OXO-4H-BENZOPYRANS, A METHOD FOR PREPARING THEM, AND THEIR USE AS ANTIDOTES | BASF AG (DE) | 1997-04-16 | — | — | EP | disclosed |