Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752341 | 0.83 | CA12 (0.55) | CA1CA2KDM4ETHRBCYP2C9 | |
| SCHEMBL11777344 | 0.81 | CA1 (0.54) | CA1CA2KDM4ETHRBCYP2C9 | |
| SCHEMBL7355901 | 0.77 | KDM4E (0.50) | CA1CA2KDM4ETHRBCYP2C9 | |
| SCHEMBL11564159 | 0.77 | CA1 (0.49) | CA1CA2KDM4ETHRBCYP2C9 | |
| SCHEMBL13543171 | 0.72 | KDM4E (0.66) | KDM4EMAOAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8802227 | 0.72 | KDM4E (0.59) | CA1CA2KDM4ETHRBCYP2C9 | |
| SCHEMBL18018242 | 0.70 | KDM4E (0.62) | CA1CA2KDM4EALDH1A1MAPT | |
| SCHEMBL19679786 | 0.69 | NPC1 (0.63) | CA1CA2KDM4ETHRBALDH1A1 | |
| Xanthone SCHEMBL27726954 | 0.69 | MAOA (0.78) | KDM4EMAOAALDH1A1GLACYP3A4 | |
| SCHEMBL13543184 | 0.69 | MAOB (0.66) | MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114560838-A | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2022-05-31 | — | — | CN | disclosed |