Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217929 | 0.80 | EPHX2 (0.46) | EPHX2FBP1CA1CA2KIF11 | |
| SCHEMBL28208229 | 0.77 | KIF11 (0.60) | FBP1CA1KIF11CA12MMP2 | |
| SCHEMBL2469875 | 0.76 | ALDH1A1 (0.49) | FBP1RAB9AMAPT | |
| SCHEMBL31732365 | 0.75 | ALDH1A1 (0.38) | CA1CA2KIF11CA12MAPT | |
| SCHEMBL29048919 | 0.75 | KIF11 (0.58) | CA1CA2KIF11MAPTCA9 | |
| SCHEMBL16230308 | 0.75 | KIF11 (0.71) | CA1CA2KIF11MAPK1MAPT | |
| Nitric Acid SCHEMBL20984887 | 0.75 | EPHX2 (0.48) | EPHX2FBP1CA1CA2KIF11 | |
| SCHEMBL4490156 | 0.75 | EPHX2 (0.44) | EPHX2FBP1CA1CA2KIF11 | |
| SCHEMBL11373063 | 0.73 | EPHX2 (0.43) | EPHX2FBP1CA1CA2KIF11 | |
| SCHEMBL6399598 | 0.73 | CTSD (0.48) | MAPK1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094267-B | Sulfonyl-substituted bicyclic compounds as ROR gamma inhibitors | 正大天晴药业集团股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111094267-A | Sulfonyl-substituted bicyclic compounds as ROR gamma inhibitors | 正大天晴药业集团股份有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-0003881-A1 | Substituted phenylnitramines, their preparation and their application as fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4130645-A | Fungicidal phenylnitramines and new phenylnitramines | AMERICAN CYANAMID COMPANY (US) | 1978-12-19 | — | — | US | disclosed |