SCHEMBL11564442

SCHEMBL11564442

O=P(O)(O)Oc1ccsn1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 11/20 0.39
INPP5A Q14642 6/20 0.39
SRC P12931 3/20 0.39
AKT1 P31749 1/20 0.39
INPP5B P32019 2/20 0.38
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
PDE3A Q14432 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BLM P54132 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28650940 0.98 INPPL1 (0.38) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL11666630 0.68 INPPL1 (0.39) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL16034397 0.67 INPPL1 (0.39) INPPL1INPP5ASRCAKT1INPP5B
Phosphoric Acid SCHEMBL28681575 0.65 LMNA (0.34) NPC1LMNARAB9AALDH1A1
SCHEMBL1697160 0.64 SRC (0.45) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL669459 0.64 INPPL1 (0.40) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL3485893 0.64 INPPL1 (0.40) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL8585187 0.62 PGK1 (0.50) NPC1LMNARAB9A
SCHEMBL3514513 0.62 SRC (0.48) INPPL1INPP5ASRCAKT1INPP5B
SCHEMBL11325002 0.62 INPPL1 (0.43) INPPL1INPP5ASRCAKT1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4155996-A PESTICIDES ROUSSEL UCLAF (FR) 1979-05-22 US disclosed
US-4128562-A PESTICIDE ROUSSEL UCLAF (FR) 1978-12-05 US disclosed
US-3983129-A INSECTICIDES ROUSSEL-UCLAF (FR) 1976-09-28 US disclosed