SCHEMBL11564684

SCHEMBL11564684

C1CN(ON2CCNCC2)CCN1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.33
MAPT P10636 1/20 0.33
PDE4A P27815 1/20 0.33
KDR P35968 1/20 0.33
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
ADRB1 P08588 3/20 0.31
HTR3E A5X5Y0 2/20 0.31
HTR3B O95264 2/20 0.31
HTR3A P46098 2/20 0.31
HTR3D Q70Z44 2/20 0.31
HTR3C Q8WXA8 2/20 0.31
SIGMAR1 Q99720 2/20 0.31
CHKA P35790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27445441 0.97 ALDH1A1 (0.35) HIF1AMAPTPDE4AKDRCA2
SCHEMBL4709193 0.88 CA2 (0.41) CA2CHKAKDM4EALDH1A1HRH1
SCHEMBL8780336 0.80
SCHEMBL27694849 0.76 HTR3E (0.32) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL1674539 0.73
SCHEMBL3326756 0.73
SCHEMBL27564161 0.73
SCHEMBL1639722 0.73
SCHEMBL27871185 0.73
SCHEMBL27375078 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106543081-B Preparation method of 1-difluoroalkylisoquinoline 四川理工学院 2020-02-18 CN claimed
CN-103920380-A Desulfurizing agent YONGQING HUAMAO BIOLOG PHARMACEUTICAL CO LTD 2014-07-16 CN claimed
CN-108473505-B Polyfluoreno [4,5-cde ] oxepine conjugates and their use in analyte detection methods 阿特生物探索公司 2019-11-05 CN disclosed
CN-108473505-A Polyfluoreno [4,5-cde ] oxepine conjugates and their use in analyte detection methods 阿特生物探索公司 2018-08-31 CN disclosed
CN-103351361-B The preparation method of LEVO CITRAZINE and dihydrochloride thereof HUASHUO TECHNOLOGY CO., LTD. (CN) 2015-07-29 CN disclosed
CN-103920380-A Desulfurizing agent YONGQING HUAMAO BIOLOG PHARMACEUTICAL CO LTD 2014-07-16 CN disclosed
CN-103351361-A Levocetirizine preparation method and levocetirizine dihydrochloride preparation method HAISO TECHNOLOGY CO LTD 2013-10-16 CN disclosed
CN-101669503-A Pesticide composition containing thiamethoxam CHENGDU HUANGPAI CROP SCIENCE 2010-03-17 CN disclosed
US-4166116-A ANTIDEPRESSANTS CANADIAN PATENTS AND DEVELOPMENT LIMITED (CA) 1979-08-28 US disclosed