⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12107964 | 0.77 | — | — | |
| SCHEMBL5874622 | 0.75 | CA2 (0.41) | — | |
| SCHEMBL5875153 | 0.75 | CA2 (0.41) | — | |
| SCHEMBL11564684 | 0.73 | HIF1A (0.33) | — | |
| SCHEMBL4958163 | 0.73 | CA2 (0.39) | — | |
| Hydrochloric Acid SCHEMBL27445441 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL4097938 | 0.71 | LMNA (0.39) | — | |
| SCHEMBL1083049 | 0.71 | CA2 (0.38) | — | |
| SCHEMBL29160731 | 0.71 | CA2 (0.33) | — | |
| SCHEMBL250579 | 0.71 | CA2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720612-A2 | CANCER TREATMENT WITH TOPOISOMERASE-II INHIBITOR, A BIS-DIOXYPIPERAZINE AND RADIATION | Topotarget A/S (DK) | 2006-11-15 | — | — | EP | claimed |
| WO-2005084754-A2 | CANCER TREATMENT WITH TOPOISOMERASE-II INHIBITOR, A BIS-DIOXYPIPERAZINE AND RADIATION | TOPOTARGET A/S (DK) | 2005-09-15 | — | — | WO | claimed |
| EP-4338737-A1 | PARP7 INHIBITOR AND USE THEREOF | Novostar Pharmaceuticals, Ltd. (CN) | 2024-03-20 | — | — | EP | disclosed |
| CN-117355516-A | Small molecules for the treatment of kinase-related diseases | 阿索斯治疗公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-109734725-B | Preparation method of piperacillin acid | 山东安舜制药有限公司 | 2021-06-01 | — | — | CN | disclosed |
| EP-2332998-B1 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | VERSUM MAT US LLC (US) | 2018-09-26 | — | — | EP | disclosed |
| CN-105229013-B | Epidithio dioxypiperazine piperazine compound or its derivative, and application thereof | 梨花女子大学校产学协力团 | 2018-09-14 | — | — | CN | disclosed |
| US-9617453-B2 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |
| EP-2308908-B1 | Aqueous dispersion of a heat hardened polyurethane composition | JANSEN BERNHARD (DE) | 2014-06-25 | — | — | EP | disclosed |
| US-20110306724-A1 | Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |
| EP-2332998-A1 | Solvent free aqueous polyurethane dispersions and methods of making and using the same | Air Products and Chemicals, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| EP-0874630-A1 | TOPOISOMERASE II POISON AND BIS-DIOXYPIPERAZINE DERIVATIVE COMBINATION THERAPY | Jensen, Peter Buhl (DK) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025044-A1 | TOPOISOMERASE II POISON AND BIS-DIOXYPIPERAZINE DERIVATIVE COMBINATION THERAPY | JENSEN PETER BUHL (DK) | 1997-07-17 | — | — | WO | disclosed |
| EP-0449041-B1 | Blends of cellulose and synthetic polymers, manufacture and uses thereof | WOLFF WALSRODE AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| EP-0449041-A2 | Blends of cellulose and synthetic polymers, manufacture and uses thereof | Wolff Walsrode Aktiengesellschaft (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0128399-B1 | SUPPORT DRESSING AND PROCESS FOR ITS MANUFACTURE | BAYER AG (DE) | 1990-07-04 | — | — | EP | disclosed |
| US-4657964-A | HYDROXYL NUMBER HALOGENATED DIOLS, DIOLS WITH CARBOXY, SULFONATE OR TERTIARY AMINE GROUPS; FIREPROOF | ICI AMERICAS INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0128399-A2 | Support dressing and process for its manufacture | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| US-4324716-A | -POLYURETHANE FOAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-3970601-A | COATINGS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |