Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566064 | 0.89 | HDAC4 (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL22746005 | 0.86 | PDE2A (0.48) | KDM4EGAAPOLBMAPTTDP1 | |
| SCHEMBL12037997 | 0.78 | PGK1 (0.42) | POLBHTTL3MBTL1 | |
| SCHEMBL29019908 | 0.76 | CCND3 (0.51) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL30395286 | 0.76 | CCND3 (0.51) | ALDH1A1KDM4EHPGDPOLBLMNA | |
| SCHEMBL9189935 | 0.73 | STK17A (0.43) | ALDH1A1POLBLMNAHTTCYP1A2 | |
| SCHEMBL29168216 | 0.71 | GRM4 (0.39) | ALDH1A1KDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL18569219 | 0.71 | CYP1A2 (0.59) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL15945548 | 0.71 | POLB (0.41) | ALDH1A1KDM4EGAASMN1; SMN2POLB | |
| SCHEMBL764317 | 0.70 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |