Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929495 | 0.88 | NR1H2 (0.49) | HPGDXDHCTSSCTSKNR1H2 | |
| SCHEMBL23915569 | 0.81 | TRPA1 (0.41) | HPGDXDHTRPA1TRPM8TRPV1 | |
| SCHEMBL14453661 | 0.81 | NFE2L2 (0.54) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL26460476 | 0.80 | GAA (0.53) | HPGDGLAPOLBGAATSHR | |
| SCHEMBL1920066 | 0.79 | HPGD (0.47) | HPGDTRPA1TRPM8TRPV1HTR2C | |
| SCHEMBL1919321 | 0.79 | HPGD (0.47) | HPGDXDHTRPA1TRPM8TRPV1 | |
| SCHEMBL27837530 | 0.79 | HPGD (0.47) | HPGDTRPA1TRPM8TRPV1RIPK1 | |
| SCHEMBL2546337 | 0.79 | HTR2C (0.47) | RIPK1HTR2CHTR2BHTR2A | |
| SCHEMBL2791295 | 0.78 | ALDH1A1 (0.53) | GLAPOLBGAATSHRHTR2C | |
| SCHEMBL23344654 | 0.78 | HPGD (0.47) | HPGDTRPA1TRPM8TRPV1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253594-A1 | OXADIAZOLOPYRAZINES AND OXADIAZOLOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2021-08-19 | — | — | US | disclosed |
| EP-3781572-A1 | OXADIAZOLOPYRAZINES AND OXADIAZOLOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS | Virginia Tech Intellectual Properties, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019204813-A1 | OXADIAZOLOPYRAZINES AND OXADIAZOLOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2019-10-24 | — | — | WO | disclosed |
| US-4166735-A | Cycloalkanecarboxanilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253594-A1 | OXADIAZOLOPYRAZINES AND OXADIAZOLOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS | NDUFAF1, OXA1L, GLS2 | HPGD 257/4885GLA 3157/4885POLB 3530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.