Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 9/20 | 0.38 |
| ▸ | CPT1A | P50416 | 2/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156617 | 0.90 | MEN1 (0.37) | PTGDR2HTR6 | |
| SCHEMBL1156485 | 0.89 | ALDH1A1 (0.35) | PTGDR2ITGB1ITGA4 | |
| SCHEMBL4569735 | 0.88 | PTGDR (0.42) | PTGDR2HTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL1156787 | 0.85 | ALOX5 (0.40) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1156754 | 0.83 | HSD17B10 (0.38) | CYP3A4SLC1A3SLC1A2SLC1A1ABCC9 | |
| SCHEMBL1156908 | 0.83 | HTR6 (0.40) | PTGDR2HTR6 | |
| SCHEMBL1156881 | 0.83 | PTGDR2 (0.39) | PTGDR2HTR6CYP3A4 | |
| SCHEMBL1156567 | 0.82 | SLC1A3 (0.34) | PTGDR2HTR6CPT1ACPT1BSLC1A3 | |
| Carbamic Acid SCHEMBL4791644 | 0.82 | HSD17B10 (0.36) | CYP3A4SLC1A3SLC1A2SLC1A1ABCC9 | |
| SCHEMBL1157008 | 0.81 | PPARG (0.42) | PTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048909-B2 | Proton pump inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-11-01 | — | — | US | disclosed |
| EP-2336107-A2 | Proton pump inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20110028476-A1 | PROTON PUMP INHIBITORS | KAJINO MASAHIRO | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028476-A1 | PROTON PUMP INHIBITORS | HRH2, HRH4, CYP2C19 | PTGDR2 606/4885HTR6 1412/4885CPT1A 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.