Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 6/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156617 | 0.90 | MEN1 (0.37) | PTGDRPTGDR2ALDH1A1MEN1LMNA | |
| SCHEMBL1156485 | 0.89 | ALDH1A1 (0.35) | PTGDR2ALDH1A1PPARG | |
| SCHEMBL1156881 | 0.89 | PTGDR2 (0.39) | PTGDRPTGDR2LMNAHTR6MMP1 | |
| SCHEMBL1156560 | 0.88 | PTGDR2 (0.39) | PTGDR2HTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL1156787 | 0.85 | ALOX5 (0.40) | ALDH1A1LMNATSHRMMP1MMP2 | |
| SCHEMBL1156754 | 0.83 | HSD17B10 (0.38) | ALDH1A1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL2418766 | 0.82 | PTGDR (0.35) | PTGDRPTGDR2ALDH1A1MEN1LMNA | |
| Carbamic Acid SCHEMBL4791644 | 0.82 | HSD17B10 (0.36) | ALDH1A1TSHRABCC9ABCC8KCNJ11 | |
| SCHEMBL1157008 | 0.81 | PPARG (0.42) | PTGDRPTGDR2ALDH1A1LMNATSHR | |
| SCHEMBL1278229 | 0.80 | LGMN (0.33) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |